-March 11, 2008
Scientists have reportedly found a mouse model to help gain better insight into human malignant mesothelioma (MM).
They hope the new model will enable them to find out more information about the progression and development of the illness.
Malignant Mesothelioma
MM is a unique form of cancer that originates in lining of the mesothelial pleural cavity and is linked to exposure to asbestos.
Although chemotherapy is currently used to treat the MM, researchers have yet to find a cure for this fatal illness.
Studies Conducted
MM has been associated with genetic lesions in humans and typically results in the loss of Neurofibromatosis type 2 or (NF2).
Researchers have reportedly found that the majority of mice with Nf2 mutations have eventually developed malignant mesothelioma.
“Our mouse models should be suitable to further dissect pathways critically important in the mesothelioma development and progression and serve as invaluable tools to test new intervention strategies,” explains Dr. Berns, a researcher from the Netherlands Cancer Institute.
(Source: Science Daily)
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